cenobamate will improve the amount or influence of diazepam by impacting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Check Intently. Take into consideration a dose reduction of CYP2C19 substrates, as clinically correct, when utilised concomitantly with cenobamate.
enasidenib will boost the level or impact of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Use Warning/Monitor. Enasidenib (a weak CYP2C19 inhibitor) could improve systemic exposure of delicate CYP2C19 substrates. Watch and alter dose of substrate as clinically indicated.
If you have any issues with the way in which your liver works, or When you've got any issues with how your kidneys get the job done.
“Ahead of I had been discharged through the medical center, a neurologist formally diagnosed me using a seizure disorder.”
quinupristin/dalfopristin will increase the stage or influence of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
crizotinib boosts amounts of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. Dose reduction may be wanted for coadministered drugs which are predominantly metabolized by CYP3A.
Oral Option: Dilute oral concentrate with water/juice/carbonated beverages or combine with semisolid foods
Tend not to consume alcohol or choose opioid medicines which make you sleepy or dizzy when having VALTOCO until finally you talk to your Health care service provider. When taken with Liquor or medicines that can cause sleepiness or dizziness, VALTOCO may perhaps make your sleepiness or dizziness worse.
acetazolamide will boost the amount or outcome of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unidentified.
“It feels great to be able to go out with self esteem and know there is one area I can perform if I sense an aura approaching or practical experience a seizure.
benzhydrocodone/acetaminophen and diazepam each enhance sedation. Stay clear of or Use Alternate Drug. Restrict use to people for whom choice treatment method solutions are inadequate
Can I consume Alcoholic beverages whilst getting dihydrocodeine? Consuming Alcoholic beverages even though you're taking dihydrocodeine might make you're feeling much more sleepy. It can also raise the risk of serious Unwanted side effects.
lasmiditan, diazepam. Both increases consequences of one other by sedation. Use Caution/Observe. Coadministration of lasmiditan as well as other CNS depressant prescription drugs, which check here includes alcohol haven't been evaluated in clinical reports. Lasmiditan could lead to sedation, in addition to other cognitive and/or neuropsychiatric adverse reactions.
If not able to stay clear of coadministration of belzutifan with sensitive CYP3A4 substrates, look at increasing the delicate CYP3A4 substrate dose in accordance with its prescribing info.